当然，风险亦不容忽视。Infigratinib是泛FGFR1-4抑制剂，对FGFR1等的抑制可能引起高磷血症等副作用。3期试验中约有4%患者出现轻度、短暂的高磷血症。在儿科长期用药的背景下，其安全性仍需更严格的监测，监管的要求也会更严格。
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As Wolves applied the seal to only their second Premier League victory of the season, Rodrigo Gomes doubling their lead over Aston Villa deep into second-half stoppage time, Rob Edwards hared down the touchline, yelling into the stands as his players started a celebratory pile-on a few yards behind him. It was a moment of catharsis for Edwards, who beat his chest and wellied an advertising hoarding, but for Unai Emery it was a different kind of cue.