简单理解，传统CAR-T细胞进入人体后，在肿瘤微环境中受到持续肿瘤抗原刺激，会出现能量代谢失衡、快速走向终末耗竭状态，导致增殖和杀伤功能下降，所以要通过较高给药剂量来实现治疗效果。
There are likely several reasons for this strategic shift. The most obvious one is the poor sales performance of PS5 games on PC, with ports generally not arriving on Steam until at least a year after their console launch. This is in stark contrast with Microsoft, which will launch first-party titles such as Fable and Forza Horizon 6 on Xbox, PC and PS5 at the same time later this year. It would see Sony return to a more Nintendo-like approach, with the latter famously (and extremely successfully) holding firm on console exclusivity for the likes of Mario, Zelda and Pokémon.
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